Molecular epidemiology of measles virus in Italy during 2008

Molecular epidemiology of measles virus in Italy during 2008

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INTRODUCTION.In view of the goal of measles elimination, it is of great importance to assess the circulation of wild-type measles virus (MV).Genetic analysis is indispensable to understand the epidemiology of measles.A large Power Rocker Recliner measles outbreak occurred in Italy in 2008, with over 4000 cases reported to the enhanced measles surveillance system introduced in 2007, 37% of which were laboratory confirmed.

METHODS.Urine and saliva samples were collected during 2008.A phylogenetic analysis of measles sequences was performed in order to understand the epidemiological situation of wild-type (MV) circulation in that period.RESULT AND DISCUSSION.

Data showed predominant circulation of the genotype D4.Genotypes A, D8, Hockey Protective - Gloves - Intermediate D9 and H1 were also detected in a small number of samples, probably representing imported cases.